Medium-term open label trial of L-carnitine in Rett syndrome
CJ Ellaway, J Peat, K Williams, H Leonard… - Brain and …, 2001 - Elsevier
Treatment strategies in Rett syndrome so far have been essentially symptomatic and
supportive. In order to establish the medium-term effects of L-carnitine, an open label trial
was performed in a cohort of 21 Rett syndrome females, with a control group of 62 Rett
syndrome females of a similar age, for a 6-month period. Compared with the Rett syndrome
controls, treatment with L-carnitine led to significant improvements in sleep efficiency (P=
0.027), especially in the subjects with a baseline sleep efficiency less than 90%, energy …
supportive. In order to establish the medium-term effects of L-carnitine, an open label trial
was performed in a cohort of 21 Rett syndrome females, with a control group of 62 Rett
syndrome females of a similar age, for a 6-month period. Compared with the Rett syndrome
controls, treatment with L-carnitine led to significant improvements in sleep efficiency (P=
0.027), especially in the subjects with a baseline sleep efficiency less than 90%, energy …
