[HTML][HTML] Should corticosteroids be used to treat biopsy-proven drug-induced acute interstitial nephritis?: PRO
A Donati, N Krishnan - Kidney360, 2022 - journals.lww.com
having lower baseline eGFRs and more severe AKI. Longer drug exposure and a delay in
initiating glucocorticoid therapy (8 versus 11 versus 35 days for complete, partial, and no
renal recovery, respectively; P50. 05) correlated with suboptimal renal recovery. Prendecki
et al.(13) evaluated the effect of steroids in a large retrospective study with a 2 year follow-up
of patients with AIN (N5187; 158 of 187 were treated with steroids, and 48 of those had DI-
AIN). Despite a lower eGFR in the steroid group compared with the nonsteroid group at the …
initiating glucocorticoid therapy (8 versus 11 versus 35 days for complete, partial, and no
renal recovery, respectively; P50. 05) correlated with suboptimal renal recovery. Prendecki
et al.(13) evaluated the effect of steroids in a large retrospective study with a 2 year follow-up
of patients with AIN (N5187; 158 of 187 were treated with steroids, and 48 of those had DI-
AIN). Despite a lower eGFR in the steroid group compared with the nonsteroid group at the …