[HTML][HTML] A multicenter, prospective, blinded, nonselection study evaluating the predictive value of an aneuploid diagnosis using a targeted next-generation sequencing …

AW Tiegs, X Tao, Y Zhan, C Whitehead, J Kim… - Fertility and sterility, 2021 - Elsevier
Objective To determine the predictive value of an aneuploid diagnosis with a targeted next-
generation sequencing–based preimplantation genetic testing for aneuploidy (PGT-A) assay
in prognosticating the failure of a successful delivery. Design Prospective, blinded,
multicenter, nonselection study. All usable blastocysts were biopsied, and the single best
morphologic blastocyst was transferred before genetic analysis. Preimplantation genetic
testing for aneuploidy was performed after clinical outcome was determined. Clinical …