[HTML][HTML] Detection of segmental aneuploidy and mosaicism in the human preimplantation embryo: technical considerations and limitations

NR Treff, JM Franasiak - Fertility and sterility, 2017 - Elsevier
Whole-chromosome aneuploidy screening has become a common practice to improve
outcomes and decrease embryonic transfer order in patients undergoing treatment for
infertility through in vitro fertilization. Despite implementation of this powerful technology, a
significant percentage of euploid embryos fail to result in successful deliveries. As
technology has evolved, detection of subchromosomal imbalances and embryonic
mosaicism has become possible, and these serve as potential explanations for euploid …