[HTML][HTML] Assessment of PI3K/AKT and MAPK/ERK pathways activation in oral lymphatic malformations
IP Gomes, LM Guimarães, TSF Pereira… - Oral Surgery, Oral …, 2022 - Elsevier
Objective Lymphatic malformations are characterized by the overgrowth of lymphatic vessels
during development. Activation of PI3K/AKT and MAPK/ERK signaling pathways occur in
isolated lymphatic malformation and in those associated with syndromes such as CLOVES
and Klippel-Trenaunay. We aimed to assess the activation of these pathways in sporadic
oral lymphatic malformations. Study Design A convenience sample of 14 formalin-fixed
paraffin-embedded samples of oral lymphatic malformations underwent …
during development. Activation of PI3K/AKT and MAPK/ERK signaling pathways occur in
isolated lymphatic malformation and in those associated with syndromes such as CLOVES
and Klippel-Trenaunay. We aimed to assess the activation of these pathways in sporadic
oral lymphatic malformations. Study Design A convenience sample of 14 formalin-fixed
paraffin-embedded samples of oral lymphatic malformations underwent …