Neonatal pulmonary hypoplasia and perinatal mortality in patients with midtrimester rupture of amniotic membranes—a critical analysis

HN Winn, M Chen, E Amon, TL Leet… - American journal of …, 2000 - Elsevier
Objective: We sought to critically assess the risk factors for neonatal pulmonary hypoplasia
and perinatal death in patients with preterm rupture of the amniotic membranes from 15 to
28 weeks' gestation. Study Design: This was a prospective cohort study. The study patients
had preterm rupture of the amniotic membranes at 15 to 28 weeks' gestation and were
without fetal anomalies, multiple gestation, and oligohydramnios before rupture of the
membranes. The amniotic fluid volume index was determined at admission and weekly …