[HTML][HTML] Regulation of lung cancer cell migration and invasion by reactive oxygen species and caveolin-1
S Luanpitpong, SJ Talbott, Y Rojanasakul… - Journal of Biological …, 2010 - ASBMB
The acquired capability of tumor cells to migrate and invade neighboring tissues is
associated with high metastatic potential and advanced stage of cancers. Recently,
signaling molecules such as reactive oxygen species (ROS) and caveolin-1 (Cav-1) have
been implicated in the aggressive behavior of cancer cells. However, the roles of specific
ROS in cancer cell migration and Cav-1 regulation are unclear. We demonstrate here that
Cav-1 plays an important role in the migration and invasion of human lung carcinoma H460 …
associated with high metastatic potential and advanced stage of cancers. Recently,
signaling molecules such as reactive oxygen species (ROS) and caveolin-1 (Cav-1) have
been implicated in the aggressive behavior of cancer cells. However, the roles of specific
ROS in cancer cell migration and Cav-1 regulation are unclear. We demonstrate here that
Cav-1 plays an important role in the migration and invasion of human lung carcinoma H460 …