[HTML][HTML] The AlphaFold database of protein structures: a biologist's guide

A David, S Islam, E Tankhilevich… - Journal of molecular …, 2022 - Elsevier
A David, S Islam, E Tankhilevich, MJE Sternberg
Journal of molecular biology, 2022Elsevier
AlphaFold, the deep learning algorithm developed by DeepMind, recently released the three-
dimensional models of the whole human proteome to the scientific community. Here we
discuss the advantages, limitations and the still unsolved challenges of the AlphaFold
models from the perspective of a biologist, who may not be an expert in structural biology.
Abstract
AlphaFold, the deep learning algorithm developed by DeepMind, recently released the three-dimensional models of the whole human proteome to the scientific community. Here we discuss the advantages, limitations and the still unsolved challenges of the AlphaFold models from the perspective of a biologist, who may not be an expert in structural biology.
Elsevier