[HTML][HTML] An apolipoprotein AV gene SNP is associated with marked hypertriglyceridemia among Asian-American patients* s⃞
CR Pullinger, BE Aouizerat, I Movsesyan… - Journal of lipid …, 2008 - ASBMB
Apolipoprotein AV (apoA-V) is an important regulator of plasma levels of triglyceride (TG) in
mice. In humans, APOA5 genetic variation is associated with TG in several populations. In
this study, we determined the effects of the p. 185Gly> Cys (c. 553G> T; rs2075291)
polymorphism on plasma TG levels in subjects of Chinese ancestry living in the United
States and in a group of non-Chinese Asian ancestry. The frequency of the less common
cysteine allele was 4-fold higher (15.1% vs. 3.7%) in Chinese high-TG subjects compared …
mice. In humans, APOA5 genetic variation is associated with TG in several populations. In
this study, we determined the effects of the p. 185Gly> Cys (c. 553G> T; rs2075291)
polymorphism on plasma TG levels in subjects of Chinese ancestry living in the United
States and in a group of non-Chinese Asian ancestry. The frequency of the less common
cysteine allele was 4-fold higher (15.1% vs. 3.7%) in Chinese high-TG subjects compared …