Liver regeneration in response to various forms of liver injury is a complex process, which
ultimately results in restoration of the original liver mass and function. Because the
underlying mechanisms that initiate this response are still incompletely defined, this study
was aimed to identify novel factors. Liver genes that were up-regulated 6 h after 70%
hepatectomy (PHx) in the rat were selected by cDNA subtractive hybridization. Besides
known genes associated with cell proliferation, several novel genes were isolated. The …