Identification of lipid binding and lipoprotein lipase activation domains of human apoAV
G Sun, N Bi, G Li, X Zhu, W Zeng, G Wu, H Xue… - Chemistry and physics …, 2006 - Elsevier
ApoAV, a newly discovered apolipoprotein, plays a key role in human triglyceride
homeostasis; however, the structure-function correlation of apoAV is not clearly understood.
To explore the relationship, wild type and six deletion mutants, that is (AV (Δ (1–51)), AV (Δ
(51–128)), AV (Δ (132–188)), AV (Δ (192–238)), AV (Δ (246–299)), AV (Δ (301–343))), of
human apoAV expressed in Escherichia coli were studied. All the deleted regions together
encompass almost the entire 343 amino acid sequence of wild type apoAV. Circular …
homeostasis; however, the structure-function correlation of apoAV is not clearly understood.
To explore the relationship, wild type and six deletion mutants, that is (AV (Δ (1–51)), AV (Δ
(51–128)), AV (Δ (132–188)), AV (Δ (192–238)), AV (Δ (246–299)), AV (Δ (301–343))), of
human apoAV expressed in Escherichia coli were studied. All the deleted regions together
encompass almost the entire 343 amino acid sequence of wild type apoAV. Circular …