Metabolic and structural impairment of skeletal muscle in heart failure
C Zizola, PC Schulze - Heart failure reviews, 2013 - Springer
C Zizola, PC Schulze
Heart failure reviews, 2013•SpringerPhysiologic endurance exercise performance is primarily limited by cardiac function. In
patients with heart failure, there is dissociation between cardiac performance and exercise
capacity, suggesting a distinct role of abnormal peripheral organ function, including skeletal
muscle function. The impact of heart failure upon skeletal muscle and exercise performance
will be discussed with a focus on molecular, structural, and functional derangements in
skeletal muscle of patients with heart failure.
patients with heart failure, there is dissociation between cardiac performance and exercise
capacity, suggesting a distinct role of abnormal peripheral organ function, including skeletal
muscle function. The impact of heart failure upon skeletal muscle and exercise performance
will be discussed with a focus on molecular, structural, and functional derangements in
skeletal muscle of patients with heart failure.
Abstract
Physiologic endurance exercise performance is primarily limited by cardiac function. In patients with heart failure, there is dissociation between cardiac performance and exercise capacity, suggesting a distinct role of abnormal peripheral organ function, including skeletal muscle function. The impact of heart failure upon skeletal muscle and exercise performance will be discussed with a focus on molecular, structural, and functional derangements in skeletal muscle of patients with heart failure.
Springer