Ovarian cancer is among the most lethal gynecologic malignancies with a poor survival
prognosis. The current therapeutic strategies involve surgery and chemotherapy. Research
is now focused on novel agents especially those targeting DNA damage response (DDR)
pathways. Understanding the DDR process in ovarian cancer necessitates having a detailed
knowledge on a series of signaling mediators at the cellular and molecular levels. The
complexity of the DDR process in ovarian cancer and how this process works in metastatic …