Purpose Patients with triple-negative breast cancer experience high rates of recurrence after
radiation, which may be facilitated by the recruitment of circulating tumor cells to
proinflammatory microenvironments in the absence of lymphocytes. We hypothesized that
patients with lymphopenia and elevated inflammatory hematologic markers after radiation
therapy would have an increased risk of locoregional failure. Methods and Materials With
approval, we retrospectively studied a cohort of women treated with adjuvant radiation …