Effect of excessive weight gain with intensive therapy of type 1 diabetes on lipid levels and blood pressure: results from the DCCT
JQ Purnell, JE Hokanson, SM Marcovina, MW Steffes… - Jama, 1998 - jamanetwork.com
Context.—Intensive treatment of type 1 diabetes results in greater weight gain than
conventional treatment. Objective.—To determine the effect of this weight gain on lipid levels
and blood pressure. Design.—Randomized controlled trial; ancillary study of the Diabetes
Control and Complications Trial (DCCT). Setting.—Twenty-one clinical centers. Participants.—
The 1168 subjects enrolled in DCCT with type 1 diabetes who were aged 18 years or older
at baseline. Intervention.—Randomized to receive either intensive (n= 586) or conventional …
conventional treatment. Objective.—To determine the effect of this weight gain on lipid levels
and blood pressure. Design.—Randomized controlled trial; ancillary study of the Diabetes
Control and Complications Trial (DCCT). Setting.—Twenty-one clinical centers. Participants.—
The 1168 subjects enrolled in DCCT with type 1 diabetes who were aged 18 years or older
at baseline. Intervention.—Randomized to receive either intensive (n= 586) or conventional …
