Isolated cervical cryptococcal lymphadenitis without meningitis in an immunocompetent human immunodeficiency virus‐negative child: a rare case report
J Gurung, WV Lyngdoh, AB Khyriem - JMM Case Reports, 2014 - microbiologyresearch.org
J Gurung, WV Lyngdoh, AB Khyriem
JMM Case Reports, 2014•microbiologyresearch.orgIntroduction: Cryptococcal infection is the second most common life‐threatening,
opportunistic infection in human immunodeficiency virus (HIV)‐infected individuals after
Mycobacterium tuberculosis. Most cryptococcal infections start in the respiratory tract and
secondarily involve the central nervous system, skin and bone marrow but rarely
disseminate to lymph nodes. Case presentation: Cases of disseminated cryptococcal
lymphadenitis with or without meningitis have been reported in HIV‐infected as well as …
opportunistic infection in human immunodeficiency virus (HIV)‐infected individuals after
Mycobacterium tuberculosis. Most cryptococcal infections start in the respiratory tract and
secondarily involve the central nervous system, skin and bone marrow but rarely
disseminate to lymph nodes. Case presentation: Cases of disseminated cryptococcal
lymphadenitis with or without meningitis have been reported in HIV‐infected as well as …
Introduction
Cryptococcal infection is the second most common life‐threatening, opportunistic infection in human immunodeficiency virus (HIV)‐infected individuals after Mycobacterium tuberculosis. Most cryptococcal infections start in the respiratory tract and secondarily involve the central nervous system, skin and bone marrow but rarely disseminate to lymph nodes.
Case presentation
Cases of disseminated cryptococcal lymphadenitis with or without meningitis have been reported in HIV‐infected as well as immunocompetent HIV‐negative individuals. Here, we report a rare case of isolated cervical cryptococcal lymphadenitis without meningitis in an immunocompetent HIV‐negative child diagnosed by fine‐needle aspiration cytology (FNAC) of the involved lymph nodes.
Conclusion
Clinical presentations of extrapulmonary cryptococcosis in HIV‐positive hosts are variable and vague. The present case scenario proves that the same might also be true for HIV‐negative individuals. FNAC is a quick, feasible, economical and reliable method for the diagnosis of cryptococcal lymphadenitis when correlated with microbiological, biochemical and histopathological examinations.
Microbiology Research