T-cell phenotypes associated with effective CAR T-cell therapy in postinduction vs relapsed multiple myeloma

AL Garfall, EK Dancy, AD Cohen, WT Hwang… - Blood …, 2019 - ashpublications.org
AL Garfall, EK Dancy, AD Cohen, WT Hwang, JA Fraietta, MM Davis, BL Levine, DL Siegel
Blood advances, 2019ashpublications.org
T-cell phenotypes associated with effective CAR T-cell therapy in postinduction vs relapsed
multiple myeloma | Blood Advances | American Society of Hematology Skip to Main Content
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Key points
  • T cells from patients early in myeloma therapy exhibit better fitness for CAR T manufacturing than those from relapsed/refractory patients.
  • CAR T cells may be more effective if manufactured from patients before onset of relapsed/refractory disease.
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