Human mesenchymal stem cells (hMSC) represent a promising cell-based therapy for a
number of degenerative conditions. Understanding the effect of aging on hMSCs is crucial
for autologous therapy development in older subject whom degenerative diseases typically
afflict. Previous investigations into the effects of aging on hMSC have proved contradictory
due to the relative narrow age ranges of subjects assessed and the exclusive reliance of in
vitro assays. This study seeks to address this controversy by using a wider range of donor …