Microglia: scapegoat, saboteur, or something else?
A Aguzzi, BA Barres, ML Bennett - Science, 2013 - science.org
A Aguzzi, BA Barres, ML Bennett
Science, 2013•science.orgMicroglia are resident immune cells in the brain and spinal cord. These cells provide
immune surveillance and are mobilized in response to disparate diseases and injuries.
Although microglial activation is often considered neurotoxic, microglia are essential
defenders against many neurodegenerative diseases. It also seems increasingly likely that
microglial dysfunction can underlie certain neurological diseases without an obvious
immune component.
immune surveillance and are mobilized in response to disparate diseases and injuries.
Although microglial activation is often considered neurotoxic, microglia are essential
defenders against many neurodegenerative diseases. It also seems increasingly likely that
microglial dysfunction can underlie certain neurological diseases without an obvious
immune component.
Microglia are resident immune cells in the brain and spinal cord. These cells provide immune surveillance and are mobilized in response to disparate diseases and injuries. Although microglial activation is often considered neurotoxic, microglia are essential defenders against many neurodegenerative diseases. It also seems increasingly likely that microglial dysfunction can underlie certain neurological diseases without an obvious immune component.
AAAS