Multiple sclerosis (MS) has recently been classified according to its clinical course. Despite
relapses and remissions, its course is invariably progressive, and the observed progression
from the remitting-relapsing to the secondary progressive form represents the accumulation
of permanent damage to the nervous system. Discussions of the nomenclatural position of
Schilder's, Marburg's, and Baló's diseases, ignore the fact that the unique, pathognomonic,
sharp-edged plaque of MS, is also the pathologic end-result in the three variants. Devic's …