[HTML][HTML] Identification and characterization of a dimerization domain in CED-6, an adapter protein involved in engulfment of apoptotic cells
HP Su, E Brugnera, W Van Criekinge, E Smits… - Journal of Biological …, 2000 - ASBMB
Phagocytosis of apoptotic cells is a key step in the completion of programmed cell death that
occurs throughout life in multicellular organisms. The molecular events involved in
clearance of apoptotic cells are just beginning to be elucidated. Recently, CED-6, an
adapter protein involved in engulfment has been cloned inCaenorhabditis elegans and in
humans. CED-6 is composed of a phosphotyrosine-binding (PTB) domain and a proline-rich
C-terminal domain with no apparent catalytic domain. Since PTB domains, originally …
occurs throughout life in multicellular organisms. The molecular events involved in
clearance of apoptotic cells are just beginning to be elucidated. Recently, CED-6, an
adapter protein involved in engulfment has been cloned inCaenorhabditis elegans and in
humans. CED-6 is composed of a phosphotyrosine-binding (PTB) domain and a proline-rich
C-terminal domain with no apparent catalytic domain. Since PTB domains, originally …
