Structure and function of human growth hormone: implications for the hematopoietins
JA Wells, AM de Vos - Annual review of biophysics and …, 1993 - annualreviews.org
JA Wells, AM de Vos
Annual review of biophysics and biomolecular structure, 1993•annualreviews.orgMolecular recognition events represent essential steps in the proper func tioning of many
critical biological processes. For instance, antibodies must bind antigens that are foreign to
an organism, but discriminate against many very similar molecules derived from the host
itself. Specific inhibitors and activators need to interact only with the proteins to which they
are directed and not with close homologues. Membrane-spanning receptors must recognize
their own specific ligand (s) and not the ligand (s) of other,
critical biological processes. For instance, antibodies must bind antigens that are foreign to
an organism, but discriminate against many very similar molecules derived from the host
itself. Specific inhibitors and activators need to interact only with the proteins to which they
are directed and not with close homologues. Membrane-spanning receptors must recognize
their own specific ligand (s) and not the ligand (s) of other,
Molecular recognition events represent essential steps in the proper func tioning of many critical biological processes. For instance, antibodies must bind antigens that are foreign to an organism, but discriminate against many very similar molecules derived from the host itself. Specific inhibitors and activators need to interact only with the proteins to which they are directed and not with close homologues. Membrane-spanning receptors must recognize their own specific ligand (s) and not the ligand (s) of other,
Annual Reviews