[HTML][HTML] A protein-restricted diet during pregnancy alters in vitro insulin secretion from islets of fetal Wistar rats
H Cherif, B Reusens, S Dahri, C Remacle - The Journal of nutrition, 2001 - Elsevier
Previous studies indicate that insulin secretion from the fetuses of dams fed a low protein
(LP) diet is reduced in response to leucine or arginine. The aim of this study was to locate
the defect in the insulin secretion pathway induced by a LP diet during gestation. The effects
of various secretagogues acting at different levels of the insulin secretion cascade were
investigated in vitro in fetal islets from dams fed either a normal or a LP diet during
pregnancy. Insulin content, insulin secretion and the cAMP content were then measured …
(LP) diet is reduced in response to leucine or arginine. The aim of this study was to locate
the defect in the insulin secretion pathway induced by a LP diet during gestation. The effects
of various secretagogues acting at different levels of the insulin secretion cascade were
investigated in vitro in fetal islets from dams fed either a normal or a LP diet during
pregnancy. Insulin content, insulin secretion and the cAMP content were then measured …