Although retinol bound to retinol-binding protein (RBP) is the most abundant retinoid form
present in the circulations of humans and most mammals, other retinoid and proretinoid
forms are also present in the blood. We are interested in understanding to what extent each
of these circulating retinoid forms contributes towards retinoid actions within cells and
tissues. Here we report two studies focused on this question. First, we examined retinoid
transport and storage in RBP-deficient mice that lack circulating RBP. These mice under …