Phospholipid transfer protein mediated conversion of high density lipoproteins generates preβ1-HDL

A von Eckardstein, M Jauhiainen, Y Huang… - … et Biophysica Acta (BBA …, 1996 - Elsevier
High density lipoproteins (HDL) subclasses can be differentiated by two-dimensional non-
denaturing polyacrylamide gradient gel electrophoresis (2D-PAGGE) and subsequent
immunoblotting. The quantitatively minor HDL-subclasses preβ1-LpA-I and γ-LpE are initial
acceptors of cell-derived cholesterol into the plasma compartment. In this study we analysed
the effect of phospholipid transfer protein (PLTP) on the electrophoretic distribution of HDL-
subclasses in plasma as well as the ability of plasma, preβ1-LpA-I, and γ-LpE to take up [3H] …