Hair growth in scalp grafts from patients with alopecia areata and alopecia universalis grafted onto nude mice
A Gilhar, GG Krueger - Archives of dermatology, 1987 - jamanetwork.com
• A basic question in both mild and severe forms of alopecia areata (AA) relates to whether
the disease is inherent to the affected tissue or secondary to circulating factors. This
question has been addressed by grafting 2-mm grafts of scalp from affected areas of seven
patients with AA or alopecia universalis (AU) onto congenitally athymic (nude) mice. Hair
growth in these grafts has been compared with that of 2-mm grafts from hairbearing skin
remnants from two individuals undergoing elective plastic surgical procedures. Because …
the disease is inherent to the affected tissue or secondary to circulating factors. This
question has been addressed by grafting 2-mm grafts of scalp from affected areas of seven
patients with AA or alopecia universalis (AU) onto congenitally athymic (nude) mice. Hair
growth in these grafts has been compared with that of 2-mm grafts from hairbearing skin
remnants from two individuals undergoing elective plastic surgical procedures. Because …
