Efficacy of influenza vaccine in nursing homes: reduction in illness and complications during an influenza A (H3N2) epidemic

PA Patriarca, JA Weber, RA Parker, WN Hall… - Jama, 1985 - jamanetwork.com
From December 10, 1982, to March 4, 1983, when influenza A (H3N2) viruses circulated in
Michigan, outbreaks of influenza-like illness were identified in seven nursing homes in
Genesee County; 272 (27%) of 1,018 residents were affected. Unvaccinated residents were
more likely than vaccinated residents to become ill (risk ratio [RR], 2.6; 95% confidence
interval [CI], 1.8-3.6) and were subsequently more likely to be hospitalized (RR, 2.4; 95% CI,
1.2-4.8), develop roentgenographically proven pneumonia (RR, 2.9; 95% CI, 1.6-5.3), or die …