[HTML][HTML] Functional complementation of BLNK by SLP-76 and LAT linker proteins
J Wong, M Ishiai, T Kurosaki, AC Chan - Journal of Biological Chemistry, 2000 - ASBMB
Recent studies have demonstrated a requirement for the SLP-76 (SH2 domain-
containingleukocyte protein of 76 kDa) and LAT (linker for activation of Tcells) adaptor/linker
proteins in T cell antigen receptor activation and T cell development as well as the BLNK
(Bcell linker) linker protein in B cell antigen receptor (BCR) signal transduction and B cell
development. Whereas the SLP-76 and LAT adaptor proteins are expressed in T, natural
killer, and myeloid cells and platelets, BLNK is preferentially expressed in B cells and …
containingleukocyte protein of 76 kDa) and LAT (linker for activation of Tcells) adaptor/linker
proteins in T cell antigen receptor activation and T cell development as well as the BLNK
(Bcell linker) linker protein in B cell antigen receptor (BCR) signal transduction and B cell
development. Whereas the SLP-76 and LAT adaptor proteins are expressed in T, natural
killer, and myeloid cells and platelets, BLNK is preferentially expressed in B cells and …
