Effects of nitric oxide on antral motility and gastric emptying in humans
JW Konturek, P Thor, W Domschke - European journal of …, 1995 - journals.lww.com
Objective: It has been suggested that nitric oxide is a nonadrenergic-noncholinergic (NANC)
inhibitory neurotransmitter released by the nerves in the gastrointestinal tract. We studied
the influence of nitric oxide on gastric emptying and antral motility using glyceryl trinitrate
(GTN), a donor of nitric oxide and L-arginine as the substrate of nitric oxide synthase.
Design: Six male volunteers (aged 21-24 years) participated in this placebo-controlled,
double-blind study. Methods: We investigated the effects of 0.8 mg sublingual GTN, 300 …
inhibitory neurotransmitter released by the nerves in the gastrointestinal tract. We studied
the influence of nitric oxide on gastric emptying and antral motility using glyceryl trinitrate
(GTN), a donor of nitric oxide and L-arginine as the substrate of nitric oxide synthase.
Design: Six male volunteers (aged 21-24 years) participated in this placebo-controlled,
double-blind study. Methods: We investigated the effects of 0.8 mg sublingual GTN, 300 …
